Friday, January 2, 2015

What is the mechanism of target cell formation?

What is the mechanism of target cell formation?



a. Precipitation of hemoglobin in the red blood cell (RBC) membrane
b. Excess cell membrane bunching up on the surface
c. Loss of membrane from protein loss
d. Cellular dehydration
e. Ankyrin and spectrin deficiency

Answer b. Excess cell membrane bunching up on the surface

Target cells are formed exclusively from excess RBC membrane. The amount of hemoglobin is too small for the size of the covering. The excess membrane “bunches up” on the cell surface.

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