Sunday, July 5, 2015

new medication and notes that his breasts have become enlarged

A male patient is placed on a new medication and notes that his breasts have become enlarged and tender to the touch. 


breast enlargement in male 


Which medication is he most likely taking?


A. Chlorthalidone.
B. Furosemide.
C. Hydrochlorothiazide.

D. Spironolactone.

E. Triamterene.



Correct answer = D. An adverse drug reaction to spironolactone is gynecomastia due to its effects on androgens and progesterone in the body. Eplerenone may be a suitable alternative if the patient is in need of an aldosterone antagonist but has a history of gynecomastia.


Spironolactone [spy-ro-no-LAC-tone] is a direct antagonist of aldosterone, thereby preventing salt retention, myocardial hypertrophy, and hypokalemia.

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