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NIMS(Nepal Index Of Medical Specialities) has been design to provide information on drugs that are marketed in Nepal by Pharma company from around the world .

NIMS DRUGS DIRECTORY

NIMS(Nepal Index Of Medical Specialities) has been design to provide information on drugs that are marketed in Nepal by Pharma company from around the world .

NIMS DRUGS DIRECTORY

NIMS(Nepal Index Of Medical Specialities) has been design to provide information on drugs that are marketed in Nepal by Pharma company from around the world .

NIMS DRUGS DIRECTORY

NIMS(Nepal Index Of Medical Specialities) has been design to provide information on drugs that are marketed in Nepal by Pharma company from around the world .

NIMS DRUGS DIRECTORY

NIMS(Nepal Index Of Medical Specialities) has been design to provide information on drugs that are marketed in Nepal by Pharma company from around the world .

Sunday, October 25, 2015

SIZE AND COLOR OF CANNULA


CANNULA SIZES THE ANSWER FOR THE QUESTION IS 20G WHICH IS DENOTED BY PINK COLOR :
PINK IS 20G CANNULA :
ORANGE  COLOR IS  16G CANNULA :

DIAGNOSE YOUR BABY :


CARDIOLOGY : 
THE SYNDROME WHICH INCLUDES CHILDHOOD ONSET OF DILATED CARDIOMYOPAHTY, NEUTROPENIA GROWTH RETARDATION WHICH IS RELATED TO MUTATIONS IN TAFAZZIN IS :

A. Turner's Syndrome
B. Kearns-Sayre Syndrome
C. Barth's Syndrome
D. MELAS Syndrome


ANS IS C : BARTH'S SYNDROME
Barth syndrome (BTHS) is an X-linked genetic condition, usually transmitted from mother to son (although there is a relatively high incidence of new mutations in Barth syndrome and one confirmed case report of a female Barth syndrome patient). A mother who is a carrier of a Barth syndrome mutation (the gene is named tafazzin — also called TAZ or G4.5) shows no signs or symptoms of this disorder herself, probably due to skewed X-chromosome inactivation.
There is a 50% chance that a boy born to a female carrier will have Barth syndrome, whereas girls born to a carrier have a 50% risk of being carriers themselves. All daughters of a male with Barth syndrome will be carriers, however no sons will be affected. Because there are proven non-carrier mothers, all mothers of Barth syndrome children should be tested in order to define the genetic risk in each family.
Any male child related through the female line to a Barth syndrome individual should be tested for the disorder, as there can be great variation in phenotype even among affected siblings.


Friday, October 16, 2015

Drug causing Pericarditis

Which Drug causes Pericarditis among 3 ?



a. Hydralazine
b. NSAID's
c. Amiodarone


ANSWER : IS A HYDRALAZINE


Some medications, including penicillin and cromolyn sodium, induce pericarditis through a hypersensitivity reaction. The anthracycline antineoplastic agents, such as doxorubicin and cyclophosphamide, have direct cardiac toxicity and can cause acute pericarditis and myocarditis.
Pericarditis can also develop from a drug-induced lupus syndrome caused by medications including procainamide, hydralazine, methyldopa, isoniazid, mesalazine, and reserpine. Methysergide causes constrictive pericarditis through mediastinal fibrosis. Dantrolene, phenytoin, and minoxidil produce pericarditis through an unknown mechanism.
Smallpox vaccination infrequently leads to myocarditis. In a review of a large vaccination program in the US military, approximately 12 per 100,000 vaccinated troops developed myopericarditis within 14 days of vaccination. Whether this was due to a direct viral cytopathic effect or an immune-mediated phenomenon is unclear.

Very common (>10% frequency) side effects include:
Hydralazine (Apresoline) is a direct-actingsmooth muscle relaxant used to treathypertension by acting as a vasodilatorprimarily in arteries and arterioles. By relaxingvascular smooth muscle, vasodilators act to decrease peripheral resistance, thereby lowering blood pressure and decreasing afterload.


However, this only has a short term effect on blood pressure, as the system will reset to the previous, high blood pressure needed to maintain pressure in the kidney necessary fornatriuresis. The long-term effect of antihypertensive drugs comes from their effects on the pressure natriuresis curve. It belongs to the hydrazinophthalazine class of drugs.


It is on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system

Monday, October 12, 2015

Goose Nect Deformity is seen in :

Goose Neck Deformity is seen in :


ans is A :
a.Endocardial AV canal defect 
b. TGA
c.Parachute mitral valve




Endocardial cushion defect

    
Endocardial cushion defect (ECD) is an abnormal heart condition. The walls separating all four chambers of the heart are poorly formed or absent. It is a congenital heart disease, which means it is present from birth.

Causes
Endocardial cushion defect occurs while a baby is still growing in the womb. The endocardial cushions are two thicker areas that go on to develop into the wall (septum) that separates the four chambers of the heart. They also form the mitral and tricuspid valves. These are the valves that separate the atria (top collecting chambers) from the ventricles (bottom pumping chambers).

BONUS QUESTION :
Least lipid soluble Beta-blocker ? a.Atenolol b.Carvedilol c.Metoprolol d.Pindolol  e.Propranolol
ans is A. Atenolol